Scientific Data Relating Chronic Fatigue Syndrome to Chronic Mercury

Summary and Analysis

U.S. Government Safe Mercury Standards, there aren't any! (the rodents are here!).

Abstracts and Reviews


The following criteria was proposed for establishing scientific proof mercury from amalgam is a cause of CFS. This criteria was sent to me by a major university hospital MD involved in research and clinical work on topics including AIDS, tuberculosis, and CFS.

He points out that anecdotes such as mine will never produce scientific proof. To gain proof:

"One would need to show, by controlled studies, that:

1. Mercury levels were higher in CFS patients than in matched controls without CFS.
2. Dental amalgams were more common in CFS patients than in controls.
3. Mercury levels correlated with the number of dental amalgams.
4. Mercury levels dropped with appropriate treatment.
5. Symptoms improved with removal of mercury and amalgams."

The Dr. also kindly sent me several research abstracts from a literature search in Medline.

The information contained "amalgam research" abstracts from various experiments at least partially aimed at the 5 points above.

I am intimately familiar with a case study of one, and have since read much deeper than many of the clearly superficial -- dental industry apologetic papers included in this page.

Presumptuously, I compare my experiences and extended knowledge to critique and validate the design of the experiments.

Interpretive commentary has been added following each abstract. At the start of the abstracts you'll find my summary and analysis. Placing the concluding commentary first is intended to spare those who prefer English over Latin, yet want to know what was said anyway.

I aim to be as objective as possible in viewing this research data. Sometimes I give opinions about the experiment design, the overlooking of the obvious, and what seems ludicrous.

In no case do I intend to be "wishing away" hard data that doesn't agree with my mercury hypothesis. As it stands, I've learned much from this information, and have further refined my mercury contentions as a result.

For those of you who don't want to muddle through all of the abstracts, again, I provide my summary and analysis first.

Before that even, I insist you read what your government has used to determine safe levels of mercury exposure for you, in the interest of preserving for your good health. It's appalling what has been done to animals to come up with such inadequate standards.


U.S. Government Safe Mercury Minimum Level Standards

The following "gif" images were published by the the environmental hazards branch of the CDC in Atlanta Georgia. (Since their tables are scans, I've chosen to have the reader view them then return to this page for commentary.)

Table 1. The effects of breathing elemental mercury on humans.

My personal experience was to have accumulated enough mercury to reach 3.4 ppm in my hair. It took longer than 8 hours for me to acquire that much, but why should that matter ? The 5.4 ppm is what was measured in the air, it doesn't reveal what was actually absorbed. My 3.4 ppm accumulated is more or less than what this amount accomplishes?

In just these short exposures, people had real problems.

As for symptoms: if "lack of ambition" means "you can't get off the sofa", then it is clear to me that chronic exposure can bring you to this exact same place. Irritability is also part and parcel with CFS.

From this we conclude that mercury amalgam fillings, proven to be continuously releasing mercury vapor into our mouths, is safe ? What do you imagine mercury amalgam out gassing mercury, abrading particles, and releasing mercury ions into your mouth over 20 years will do for you ?

Table 2. The effects of breathing elemental mercury vapor on rodents.

Why do we know so much more about the rodent effects ? Because after you expose them, you dissect them, and look at what you have done. Obviously you can't do this to humans.

They used exposure levels equivalent to the buildup in my 1995 hair (3.4 ppm mercury) to expose these poor little creatures for one hour. The result: devastating consequences to their major body organs.

There's likely to be a difference from humans in the issue of body mass differences. Mass increases as a cubic function when you increase up to human size. We can probably withstand more than these small animals. The point not to forget is that mercury is doing damage at all levels of exposure.

The longer term exposures only get worse for rodents.

Notice that there are no safe levels demonstrated over any amount of time. I don't see the evidence for the minimum safe level! Even a small amount, if concentrated in nerve or immune cells, could be devastating. If the cause of an autoimmune response, more than plenty!

Table 3. The effects of breathing organic mercury vapor on humans.

There is no information here.

Table 4. The effects of breathing organic mercury vapor on rodents.

There is no information here either.

Table 5. The effects of eating and drinking elemental mercury on humans.

The great human knowledge void appears! From this we conclude that mercury amalgam fillings, proven to dissolve, erode, crumble, and fall out of our teeth into our mouth and GI track is safe ?

Table 6. The effects of eating and drinking elemental mercury on rodents.

Kidney problems, immune problems, changes of behavior, death of young, where can I get some of this for myself ? Instant availability for "100+ million satisfied mercury amalgam dental patients".

Table 7. The effects of eating and drinking organic mercury on humans.

The human knowledge void continues! From this we conclude that mercury amalgam fillings, proven to dissolve, erode, crumble, and fall out of our teeth into our mouth and GI track, where untold numbers of microorganisms are capable of converting the mercury to methyl mercury, is safe ?


Table 8. The effects of eating and drinking organic mercury on rodents.

Two years in a rabbit is what to a human ? Mothers, beware your children. You may have CFS, but that same mercury may do much worse to your offspring.



Summary and Analysis

1. There is clear and compelling research data to demonstrate that mercury escaped from mercury amalgam fillings contribute measurable mercury to the body tissues and urine stream.

2.
DMPS administration is a demonstrated means for increasing mercury outflow from the body tissues to the urine stream.

3.
A number of researchers have gone to great effort to prove that the mercury amalgam population at large doesn't have health problems that might be related to mercury. A fact supported by the top line analysis that 99.5% don't have CFS.

For those of us who remain undeterred in suspecting mercury, this data leads us to wonder why some people are poisoned and others not ? Simply put, it's the direction of inequality of mercury intake rates vs excretion rates.

4. While cognitive and physical manifestations of CFS from mercury toxicity are relegated to possibly existing in only 0.5% of the amalgam population, emotions are a different story.

At least among women, mercury amalgam appears to be giving a significant number of them more fatigue, insomnia, anxiety, anger and depression.

Does this also explain why dentists who literally work and breath mercury daily have historically higher suicide rates than the general public?

5. While dismissing a 14 day, 3 month waiting time period chelation as a cure, the DMSA study, along with the angry women study, both hinted at meaningful fatigue effects.

The DMSA patients who got the "real stuff" showed a meaningful alleviation of fatigue. The women with mercury amalgam fillings expressed having more fatigue and insomnia than the control group. When considering CFS causes, anything affecting fatigue gets our attention.

6. There is a serious void in the research literature of well designed experiments aimed at determining if mercury is a root cause for people suffering from CFS. There are no proven safe levels of mercury exposure for humans.

You can rightly argue that there are no unsafe levels proven either. However, the effects on our poor little animal friends should put fear in anyone that has ever had a mercury amalgam filling.

Lets revisit the research MD's criteria for establishing scientific proof that mercury causes CFS:

An amendment to the research MD's criteria is to change requirement #1 to "Toxicity enabling cofactors are correlated in the CFS group, but not in the larger amalgam population"..

My reasoning is that as a statistical population, everyone with mercury amalgam fillings has potential to see similar mercury exposure rates. Nominal exposure rates will vary with fillings according to size, surface area and number. Yet only 0.5% are suffering from full fledged CFS. There has to be more to the story of mercury toxicity in the CFS group.

Point 2 below is a futile question, since WHO reports that 98% of adult Americans between 35 & 45 have amalgam filling experience. Proving that fillings in one group are more common than another when you know that 98% of all have them will produce no information.

My problem with criteria numbers 2 & 3 is that there isn't a mathematically proportional indicator for determining the true body burden of mercury. The harmfully bound mercury is not in the hair, floating in the blood, or coming out in urine, even with a DMPS challenge.

Current diagnostics can only show if a mercury elevation is likely, but not the true magnitude of that elevation.


"One would need to show, by controlled studies, that:

1. "Toxicity enabling cofactors are correlated in the CFS group, but not in the larger amalgam population".
2. Dental amalgams were more common in CFS patients than in controls.
3. Mercury levels correlated with the number of dental amalgams.
4. Mercury levels dropped with appropriate treatment.
5. Symptoms improved with removal of mercury and amalgams."

The abstracts in this page provide the following answers:

#1 - no data
#2 - no data, and none possible.
#3 - Demonstrated, to the extent that urine levels followed the number of fillings in healthy people.
#4 - Demonstrated, to the extent that urine levels followed the number of fillings in healthy people.
#5 - Inconclusive, restorative nutrition and extended recovery times are missing from all of these studies.

The quest for scientific proof must continue. The picture of scientific facts is not yet filled in to prove or disprove that mercury from amalgams is a cause of illness in the 0.5% of the amalgam population with CFS.

We are certain that the mercury dental fillings are exposing the entire population bearing them to mercury, a proven toxin. We are certain that similar levels of accumulative mercury exposure are creating devastating effects in rodents.

You are chronically ill with CFS symptoms for 11 years, have had all other known root causes of illness examined and eliminated. You have demonstrated an elevation of body mercury through a DMPS "challenge". Should you take a chance that mercury is the root cause?

That was the decision I was faced with in early 1995. You have to decide for yourself.

I took the gamble, I won. I became well, it appears in my case that it was indeed the mercury.


Long-term mercury excretion in urine after removal of amalgam fillings.
Begerow-J; Zander-D; Freier-I; Dunemann-L. Int-Arch-Occup-Environ-Health.
1994; 66(3): 209-12 .

The long-term urinary mercury excretion was determined in 17 28- to 55-year-old persons before and at varying times (up to 14 months) after removal of all (4-24) dental amalgam fillings. Before removal the urinary mercury excretion correlated with the number of amalgam fillings. In the immediate post-removal phase (up to 6 days after removal) a mean increase of 30% was observed. Within 12 months the geometric mean of the mercury excretion was reduced by a factor of 5 from 1.44 micrograms/g (range: 0.57-4.38 micrograms/g) to 0.36 microgram/g (range: 0.13-0.88 microgram/g). After cessation of exposure to dental amalgam the mean half-life was 95 days. These results show that the release of mercury from dental amalgam contributes predominantly to the mercury exposure of non-occupationally exposed persons. The exposure from amalgam fillings thus exceeds the exposure from food, air and beverages. Within 12 months after removal of all amalgam fillings the participants showed substantially lower urinary mercury levels which were comparable to those found in subjects who have never had dental amalgam fillings. A relationship between the urinary mercury excretion and adverse effects was not found. Differences in the frequency of effects between the pre- and the post-removal phase were not observed.

Comments

1. First of all, lets end the debate on whether mercury amalgam fillings contribute mercury to your body chemistry right here. The study above shows quite clearly they do.

2. As I experienced it, having my fillings changed was a trigger. If the metal is excreting at a 30% higher rate, can we assume it is being absorbed at a higher rate also ?

3. It's not the mercury coming out in urine that is causing health problems. It is the metal stuck in/to important cells in the body that has negative effects.

4. I wouldn't expect anyone chronically ill to get better based on simply removing amalgam, not without a subsequent and thorough set of chelation treatments over some months.


DMSA administration to patients with alleged mercury poisoning from
dental amalgams: a placebo-controlled study. Sandborgh-Englund-G;
Dahlqvist-R; Lindelof-B; Soderman-E; Jonzon-B; Vesterberg-O; Larsson-KS .
J-Dent-Res. 1994 Mar; 73(3): 620-8 .

The present investigation was performed to determine the effect of 14-day oral administration of meso-2.3-dimercaptosuccinic acid (DMSA) on the urinary mercury excretion and the potential reduction of blood and plasma mercury concentrations, and also to relate these effects to possible decrease of symptoms, allegedly associated with amalgam fillings. Twenty subjects, relating their symptoms to mercury from amalgam fillings, received 20 mg/kg DMSA or placebo for 14 days. Their symptoms and mood states were recorded during the study and at a check-up 3 months later. Interpretation was based on intra-individual differences. DMSA-treatment resulted in an average increase in urinary mercury excretion by 65% and a decrease in blood mercury levels of 0.04 microgram/L/day. At the check-up after 3 months, urinary mercury excretion had returned to the pre-treatment level. No treatment effect of DMSA was apparent on subjective symptoms and mood state.

One statistically significant treatment effect was noted-a decrease in fatigue-inertia in the DMSA-group-but there was no demonstrable correlation with increased urinary excretion or decreased blood concentration of mercury. Three subjects showed hypersensitive reactions, probably DMSA specific, at the end of the treatment period. This placebo-controlled study provides no scientific support for diagnostic or therapeutic administration of DMSA for symptoms allegedly associated with chronic mercury exposition from dental amalgam fillings.

Comments

1. What was the amalgam status ? Did they or did they not remove the amalgam first? It doesn't appear that mercury body burden was established at the start either.

2. The time periods and number of treatments are way off what I experienced. I had 6 DMPS treatments spaced over a year, with the first 5 averaging every 6 weeks. At the end of 14 days, and at the end of 3 months, I would not have been able to claim any major improvements either. In fact, I suspect that at the end of 14 days, a bunch of these guys felt even worse. It was some days after restorative vitamin & mineral IV that I recuperated from the treatment. Actual recovery to a higher state of wellness took even longer after chelation.

3. Very interesting CFS suffers: "One statistically significant treatment effect was noted-a decrease in fatigue-inertia in the DMSA-group..."

4. What this proves to me is that one 14 day burst of intense chelation treatment is not likely to cure anyone of mercury poisoning in a 3 month time period.


Human studies with the chelating agents, DMPS and DMSA. Aposhian-HV;
Maiorino-RM; Rivera-M; Bruce-DC; Dart-RC; Hurlbut-KM; Levine-DJ; Zheng-W;
Fernando-Q; Carter-D; et-al . J-Toxicol-Clin-Toxicol. 1992; 30(4): 505-28 .

Meso-2,3-dimercaptosuccinic acid (DMSA) is bound to plasma albumin in humans and appears to be excreted in the urine as the DMSA-cysteine mixed disulfide. The pharmacokinetics of DMSA have been determined after its administration to humans po. For the blood, the tmax and t1/2 were 3.0 h + 0.45 SE and 3.2 h + 0.56 SE, respectively. The Cmax was 26.2 microM + 4.7 SE. To determine whether dental amalgams influence the human body burden of mercury, we gave volunteers the sodium salt of 2,3-dimercaptopropane-1-sulfonic acid (DMPS). The diameters of dental amalgams of the subjects were determined to obtain the amalgam score. Administration of 300 mg DMPS by mouth increased the mean urinary mercury excretion of subjects over a 9 h period. There was a positive correlation between the amount of mercury excreted and the amalgam score. DMPS might be useful for increasing the urinary excretion of mercury and thus increasing the significance and reliability of this measure of mercury exposure. DMSA analogs have been designed and synthesized in attempts to increase the uptake by cell membranes of the DMSA prototype chelating agents. The i.v. administration of the monomethyl ester of DMSA, the dimethyl ester of DMSA or the zinc chelate of dimethyl DMSA increases the biliary excretion of platinum and cadmium in rats.

Comments

1. This experiment is clear in demonstrating that mercury amalgam contributes directly to the amount of mercury, a known toxin, held within your body.

2. My MD's position on DMPS as a diagnostic tool is supported here.


Urinary mercury after administration of 2,3-dimercaptopropane-1-sulfonic
acid: correlation with dental amalgam score. Aposhian-HV; Bruce-DC;
Alter-W; Dart-RC; Hurlbut-KM; Aposhian-MM . FASEB-J. 1992 Apr; 6(7): 2472-6 .

There is considerable controversy as to whether dental amalgams may cause systemic health effects in humans because they liberate elemental mercury. Most such amalgams contain as much as 50% metallic mercury. To determine the influence of dental amalgams on the mercury body burden of humans, we have given volunteers, with and without amalgams in their mouth, the sodium salt of 2,3-dimercaptopropane-1-sulfonic acid (DMPS), a chelating agent safely used in the Soviet Union and West Germany for a number of years. The diameters of dental amalgams of the subjects were determined to obtain the amalgam score. Administration of 300 mg DMPS by mouth increased the mean urinary mercury excretion of the amalgam group from 0.70 to 17.2 micrograms and that of the nonamalgam group from 0.27 to 5.1 micrograms over a 9-h period. Two-thirds of the mercury excreted in the urine of those with dental amalgams appears to be derived originally from the mercury vapor released from their amalgams. Linear regression analysis indicated a highly significant positive correlation between the mercury excreted in the urine 2h after DMPS administration and the dental amalgam scores. DMPS can be used to increase the urinary excretion of mercury and thus increase the significance and reliability of this measure of mercury exposure or burden, especially in cases of micromercurialism.

Comments

1. This experiment is also clear in demonstrating that mercury amalgam contributes to the amount of mercury held within your body.

2. My MD's position on DMPS as a diagnostic tool is further supported here.


Dental amalgam and cognitive function in older women: findings from the
Nun Study. Saxe-SR; Snowdon-DA; Wekstein-MW; Henry-RG; Grant-FT; Donegan-SJ; Wekstein-DR. J-Am-Dent-Assoc. 1995 Nov; 126(11): 1495-501 .

The authors determined the number and surface area of occlusal dental amalgams in a group of 129 Roman Catholic sisters who were 75 to 102 years of age. Findings from this study of women with relatively homogeneous adult lifestyles and environments suggest that existing amalgams are not
associated with lower performance on eight different tests of cognitive function.

Comments

1. Okay. But we already know that occurrence of CFS in mercury amalgam patients is not greater than 0.5%. 500,000/100,000,000. Randomly select 100 mercury amalgam patients and you have at best a 50% chance that just one of them is demonstrating CFS symptoms.


Concentrations of blood, serum and urine components in relation to number
of amalgam tooth fillings in Swedish women. Ahlqwist-M; Bengtsson-C;
Lapidus-L; Lindstedt-G; Lissner-L . Community-Dent-Oral-Epidemiol. 1995
Aug; 23(4): 217-21 .

Altogether 1462 women aged 38, 46, 50, 54 and 60 yr were examined in 1968/69 in a combined medical and dental population study in Gothenburg, Sweden. Number of tooth surfaces restored with amalgam fillings was assessed. The examination was repeated in 1980/81 including a new dental examination. The results from a number of biochemical analyses of blood, serum and urine were analyzed for a possible statistical relationship to number of dental amalgam fillings. As emphasis has been put in the literature on special influence from amalgam on kidney function and on the immunological system, special attention was paid to variables which might reflect these functions in our analyses. When potential confounders were taken into consideration, no significant correlations remained which seemed to be of clinical importance. Specifically, amalgam fillings were not found to be associated with impairment of the kidney function or the immunological status.

Comments


1. Again, we already know that occurrence of CFS in mercury amalgam patients is not greater than 0.5%. Most people with mercury amalgam are not suffering mercury suspicious health problems, this fact is well established.

2. We need to be focusing on the populations of sick people. This is a 3-sigma problem. Random, population at large studies are never going to add new knowledge to low level mercury toxicology.


Mercury, dental amalgam fillings and intellectual abilities in Inuit
school children in Greenland. Tulinius-AV . Arctic-Med-Res. 1995 Apr;
54(2): 78-81 .

The hair mercury concentration of 125 Greenland pupils aged 12 to 17 was recorded and compared with the pupils' marks in selected school subjects. Mercury values ranged from 0.2 to 15.9 microgram per gram (micrograms/g) and 20% of the pupils had more than 6 micrograms/g. There was no correlation between a high mercury concentration score and poor results in school. Correlation of the number of dental amalgam fillings with mercury concentration showed a weak trend but no significant relation. Eating habits were significantly correlated with mercury concentration. Girls had a significantly higher number of amalgam fillings than boys, and had a significantly higher mercury concentration. Modern Inuit and the mummified Qilaqitsoq Inuit from the 15th century had largely identical levels of mercury in the hair irrespective of today's higher exposure to global environmental contamination. This is believed to result from a change in eating habits away from the traditional Greenland food towards a more continental diet.

Comments

1. Again, we already know that occurrence of CFS in mercury amalgam patients is not greater than 0.5%. Most people with mercury amalgam are not suffering mercury suspicious health problems, this fact is well established.

2. We need to be focusing on the populations of sick people. This is a 3-sigma problem. Random, population at large studies are never going to add new knowledge to low level mercury toxicology.


Dental amalgam, low-dose exposure to mercury, and urinary proteins in
young Swedish men. Herrstrom-P; Schutz-A; Raihle-G; Holthuis-N;
Hogstedt-B; Rastam-L . Arch-Environ-Health. 1995 Mar-Apr; 50(2): 103-7 .

Chronic exposure to inorganic mercury can cause kidney injury. Evidence gained from occupational medicine indicates that individuals who are exposed to only environmental sources, including amalgam tooth fillings, are at very little risk. Animal experiments, however, have revealed glomerular lesions of immunologic origin after low-dose exposure to inorganic mercury. In this study, the association between the number of amalgam tooth surfaces, urinary mercury, and proteinuria was explored in a sample of 48 randomly selected, apparently healthy male students who were 17-22 y of age. Presence of any of the following proteins in two separate urine samples was considered to be potentially indicative of any tubular and/or glomerular lesion: albumin, alpha-1-microglobulin (HC-protein), kappa and lambda light chains, and N-acetyl-beta-D-glucosaminidase. No significant relationship was found between any of the proteins and amalgam or urinary mercury. The results of this study did not suggest that amalgam fillings cause kidney dysfunction in humans.

Comments

1. Again, we already know that occurrence of CFS in mercury amalgam patients is not greater than 0.5%. Most people with mercury amalgam are not suffering mercury suspicious health problems, this fact is well established.

2. We need to be focusing on the populations of sick people. This is a 3-sigma problem. Random, population at large studies are never going to add new knowledge.

3. What is the mean age for developing CFS ? Taking 17-22 year olds is looking at individuals at the prime of life and vitality.


Determination of blood mercury concentrations in Alzheimer's patients.
Fung-YK; Meade-AG; Rack-EP; Blotcky-AJ; Claassen-JP; Beatty-MW; Durham-T .
J-Toxicol-Clin-Toxicol. 1995; 33(3): 243-7 .

Trace element neurotoxicity can be an etiologic factor for Alzheimer's disease. This cross sectional clinical study determined blood mercury in patients with diagnosed Alzheimer's disease as compared to control subjects without known central nervous system and renal disorders. Unique within the confines of a nursing home, all subjects were exposed to the same environment and consumed a diet without fish and seafood for a period of three months prior to the study. The results of this study show that blood mercury concentrations detected in subjects with Alzheimer's disease were not statistically different than that of control subjects. Ratios of blood mercury to blood selenium were also determined and no statistical difference was found between these two groups.

Comments

1. I'd like to see this experiment done again using the DMPS "challenge".

2. My understanding of Alzheimers is that it is a "brain disease", not a "blood disease". If mercury is chemically lodged in brain nerve cells, it does not follow that it will also be floating in the blood in the same proportion.

3. The mercury in my hair, remaining in my fillings, coming out in my urine, and floating in my blood is not the mercury making me sick.


Renal effect of mercury from amalgam fillings. Eti-S; Weisman-R;
Hoffman-R; Reidenberg-MM . Pharmacol-Toxicol. 1995 Jan; 76(1): 47-9 .

The current study was to answer the question: Is enough mercury absorbed from dental amalgam fillings to produce renal damage? One hundred healthy adults (18-44 years old) filled out health questionnaires and voided urine samples. Urine mercury concentration and N-acetyl-beta-glucosaminidase (NAG) were measured. Subjects were grouped into those having amalgam fillings (N =66) and those without (N = 34). Median (95% Confidence Interval) urine mercury was 1 (1-2) and 0 (0-0.6) ng/ml (P < 0.01) and median urine NAG was 23 (18-27) and 16 (11-18) units (P < 0.05) in the two groups respectively. People with mercury amalgam fillings excreted slightly more mercury than people without them, and have a very small increase in urinary NAG excretion that is of no clinical significance. This dose of mercury absorbed from amalgam appears to be too little to be a public health hazard for renal injury.

Comments


1. Again. We already know that occurrence of CFS in mercury amalgam patients is not greater than 0.5%. Most people with mercury amalgam are not suffering mercury suspicious health problems, this fact is well established.

2. We need to be focusing on the populations of sick people. This is a 3-sigma problem. Random, population at large studies are never going to add new knowledge.

3. 99.5% of people appear to suffer this level of exposure to the toxin just fine. When 0.5% of the amalgam population is 500,000 people and you are one of those, 99.5% just isn't "good enough".


Effect of mercury from dental amalgams on mercury concentration in urine.
Ulukapi-I; Cengiz-S; Sandalli-N . J-Nihon-Univ-Sch-Dent. 1994 Dec; 36(4):
266-8 .

A study was conducted to determine the mercury concentration in urine after placement of dental amalgam restorations. The 24-h urine mercury levels in 10 children with a mean age of 8 years were determined before the amalgam restorations had been placed, and after placement. The urinary
mercury content was measured by the cold vapor atomic fluorescence method. Mercury levels in the urine samples before placement of the amalgam restorations were below the detection limit, and the values obtained after placement, although detectable, were far below the limits stipulated by the World Health Organization. Under the conditions of this study, it is considered that the mercury levels released from dental amalgams are not high enough to cause any systemic toxic effect.

Comments

1. Amalgam fillings are a definite source of mercury to the body.

2. Wait a minute here! There is no evidence in this study to jump to a conclusion on long term systemic toxicity effects. I personally have 20+ years invested in accumulating mercury this way.

3. Mercury poisoning from amalgam is a slow accumulative process. If the negative results of placing a filling were immediate, I wouldn't be writing this, and there wouldn't be any children having a known toxin, #3 on the EPA's list, placed in their teeth in 1994.

4. What century is this ? We put a known toxin in the teeth of our children, none become sick immediately, we pat ourselves on the back "good job", and go have a beer to celebrate ?


Psychometric evidence that mercury from silver dental fillings may be an
etiological factor in depression, excessive anger, and anxiety.
Siblerud-RL; Motl-J; Kienholz-E . Psychol-Rep. 1994 Feb; 74(1): 67-80 .

Scores on the Beck Depression Inventory were compared for 25 women who had silver dental fillings (amalgams) and for 23 women without amalgams. Women with amalgams had significantly higher scores and reported more symptoms of fatigue and insomnia. Anger scores from the State-Trait Anger Expression Inventory showed that the women with amalgams had statistically significantly higher mean scores on expressing anger without provocation and experiencing more intense angry feelings. The women without amalgams scored significantly higher on controlling anger, which suggested they invested more energy in monitoring and preventing the experience and expression of anger. Anxiety scores from the State-Trait Anxiety Inventory showed the women with amalgams scored significantly less pleasant, satisfied, happy, secure, and steady, and had a more difficult time making decisions. They had significantly higher Trait Anxiety scores. The women with amalgams also had significantly higher levels of mercury in the oral cavity before and after chewing gum. The study suggests that amalgam mercury may be an etiological factor in depression, excessive anger, and anxiety because mercury can produce such symptoms perhaps by affecting the neurotransmitters in the brain.

Comments

1. This study goes against my nag that 99.5% have no mercury caused health problems. The angle here is different from the other studies in that it is essentially measuring emotions, and not cognitive, physical or biochemical metrics. Though the fatigue jumps out at a recovered CFS sufferer.

2. As a recovered CFS sufferer, I know about unstable emotions and anxiety. This study connects with me. It demonstrates a set of symptoms that affects a much larger portion of the population.


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